Modeling Excitable Tissue
نویسندگان
چکیده
منابع مشابه
Boundary-induced reentry in homogeneous excitable tissue.
Heterogeneity of cardiac electrical properties can lead to heart rhythm disorders. Numerical studies have shown that stimuli chosen to maximize dynamic heterogeneity terminate wave propagation. However, experimental investigations suggest that similar sequences induce fragmentation of the wave fronts, rather than complete wave block. In this paper we show that an insulating boundary in an other...
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Tamás Szakály, István Lagzi, Ferenc Izsák ∗and András Volford a Department of Physical Chemistry, Eötvös University, P.O. Box 32, Budapest H-1518, Hungary b Department of Applied Mathematics, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands c Department of Applied Analysis and Computational Mathematics, Eötvös University, P.O. Box 120, Budapest H-1518, Hungary d Department ...
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To understand how excitable tissues give rise to arrhythmias, it is crucially necessary to understand the electrical dynamics of cells in the context of their environment. Multicellular monolayer cultures have proven useful for investigating arrhythmias and other conduction anomalies, and because of their relatively simple structure, these constructs lend themselves to paired computational stud...
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We propose a new biological framework, spatial networks of hybrid input/output automata (SNHIOA), for the efficient modeling and simulation of excitable-cell tissue. Within this framework, we view an excitable tissue as a network of interacting cells disposed according to a 2D spatial lattice, with the electrical behavior of a single cell modeled as a hybrid input/ouput automaton. To capture th...
متن کاملSpatiotemporal dynamics of damped propagation in excitable cardiac tissue.
Compared to steadily propagating waves (SPW), damped waves (DW), another solution to the nonlinear wave equation, are seldom studied. In cardiac tissue after electrical stimulation in an SPW wake, we observe DW with diminished amplitude and velocity that either gradually decrease as the DW dies, or exhibit a sharp amplitude increase after a delay to become an SPW. The cardiac DW-SPW transition ...
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ژورنال
عنوان ژورنال: Simula SpringerBriefs on computing
سال: 2021
ISSN: ['2512-1677', '2512-1685']
DOI: https://doi.org/10.1007/978-3-030-61157-6